Part:BBa_K4739001:Design

Minihepcidin, a treatment for encouragement of erythropoiesis

Assembly Compatibility:

• 10
  COMPATIBLE WITH RFC[10]
• 12
  COMPATIBLE WITH RFC[12]
• 21
  COMPATIBLE WITH RFC[21]
• 23
  COMPATIBLE WITH RFC[23]
• 25
  COMPATIBLE WITH RFC[25]
• 1000
  COMPATIBLE WITH RFC[1000]

Design Notes

1. Choose codons that are frequently used in the host organism to ensure efficient translation. 2. Optimize for codons corresponding to abundant tRNAs in the host to enhance translation speed. 3. Limit repetitive DNA sequences that may lead to recombination events and genomic instability.

Source

No source for this sequence, we designed it from the amino acid sequence.

References

1. Casu, C.; Paraskevi Rea Oikonomidou; Chen, H.; Nandi, V.; Ginzburg, Y.; Prasad, P.; Fleming, R.E.; Shah, Y.M.; Valore, E.V.; Nemeth, E.; et al. Minihepcidin Peptides as Disease Modifiers in Mice Affected by β-Thalassemia and Polycythemia Vera. Blood 2016, 128, 265–276, doi:https://doi.org/10.1182/blood-2015-10-676742.